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Geroscience in heart failure: the search for therapeutic targets in the shared pathobiology of human aging and heart failure
Finding treatment targets by studying the shared aging processes in heart failure
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Abstract
Age is a major risk factor for heart failure, but emerging evidence suggests the biology of aging may be intervenable.
- The biology of aging could be modified to address age-associated chronic diseases like heart failure.
- Human omics has provided insights into the shared biological mechanisms of aging and heart failure.
- Identifying relevant mechanisms of aging biology could lead to targeted therapies for heart failure.
- A human-first approach in Geroscience may enhance the development of treatments for heart failure.
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