Revue medicale suisse

Glucagon-like peptide-1 drugs and heart failure

Updated

Abstract

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are associated with a reduced risk of cardiovascular events in high-risk diabetes patients.

  • GLP-1 RAs have shown benefits in obese patients with cardiovascular disease, even without diabetes.
  • Semaglutide and tirzepatide may lead to fewer heart failure hospitalizations in patients with preserved or mildly reduced ejection fraction.
  • These medications could improve symptoms and functional capacity in obese patients with heart failure.
  • Current data on GLP-1 RAs in heart failure with reduced ejection fraction remain limited.

Simplified

Funding

Competing interests

Les auteurs n’ont déclaré aucun conflit d’intérêts en relation avec cet article
PubMed

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