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Abstract
GLP-1 receptor agonists (GLP-1RAs) may improve inflammatory skin conditions and wound repair.
- GLP-1RAs are linked to anti-inflammatory and proreparative mechanisms that could benefit skin health.
- Their use might be associated with injection-site reactions and skin hypersensitivity.
- There is potential for rare autoimmune blistering disorders as adverse effects.
- Clinically significant facial volume loss and skin laxity may occur with pharmacologic weight reduction.
- Evidence supporting the effects of GLP-1RAs on skin biology is primarily observational and mechanistic, with few dermatology-specific randomized trials.
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