Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]May 29, 2026

Use of GLP-1 Receptor Drugs in Male Cosmetic Treatments: Options for Skin Surgeons

GLP-1 Therapies Weekly Brief ↗PubMed ↗DOI ↗

Updated May 30, 2026

Abstract

Concerns driving male aesthetic treatment requests may overlap with secondary skin effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs).

Men seeking aesthetic treatments may experience hair loss, changes in facial and body volume, and skin quality and laxity as side effects of GLP-1RA use.
Management options for these concerns include dermal fillers for restoring volume and biostimulatory agents for improving skin laxity.
Medical and procedural interventions for hair loss are also available as treatment options.
Dermatologic surgeons play a critical role in addressing these aesthetic concerns associated with GLP-1RA treatments.

Simplified

BACKGROUND AND OBJECTIVES: The demand for male aesthetic treatments continues to rise, and with increased utilization of the glucagon-like peptide-1 receptor agonists (GLP-1RAs), we anticipate a growing need to address these concerns. This narrative review examined the intersection of skin-related effects of GLP-1RAs and male aesthetics, focusing on the role of the dermatologic surgeon in their management.

METHODS: A search of the available peer-reviewed literature through March 2026 in the PubMed database was conducted. Search terms included combinations of terms related to GLP-1RAs, male aesthetics, and dermatologic treatments. Studies were included if they were peer-reviewed, published in English, and relevant to the topic.

RESULTS: Many concerns that drive men to seek aesthetic treatments overlap with secondary cutaneous manifestations of GLP-1RA treatments including hair loss, changes in facial and body volume, and skin quality and laxity. Management options include, but are not limited to, dermal fillers for volume restoration and biostimulatory agents for skin laxity, along with medical and procedural interventions for hair loss.

CONCLUSION: Dermatologic surgeons are well-positioned to address GLP-1 receptor agonist-related aesthetic concerns in male patients. Practitioners should be prepared to offer evidence-based, customized treatment strategies as this population grows.

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Funding

Competing interests

A. Minokadeh serves as a consultant and investigator for Allergan Aesthetics, a speaker for Evolus, Inc., and consultant and investigator for Merz Aesthetics. H. Badalian reports no conflicts of interest.

PubMed

Use of GLP-1 Receptor Drugs in Male Cosmetic Treatments: Options for Skin Surgeons

Abstract

Full Text

Funding

Competing interests

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Abstract

Full Text

Funding

Competing interests

Related papers

You found one interesting study. We’ll send the next 7.

What Lands in Your Inbox Each Week:

Recent issues from the glp-1 therapies brief