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Abstract
Topical skincare formulations may improve facial and body skin quality and sagging/laxity after rapid weight loss.
- Diminished skin quality and sagging can occur following rapid weight loss associated with glucagon-like peptide-1 receptor agonists (GLP-1RAs).
- GLP-1RA treatment may lead to dehydration and nutrient deficiencies in subcutaneous adipose tissues and the dermal extracellular matrix.
- Reduced fibroblast function may result in decreased collagen production and increased degradation of collagen and elastic fibers.
- Recent skincare research has identified growth factors, peptides, and botanical extracts that could rejuvenate skin.
- Clinical studies have shown that topical formulations may effectively improve sagging and laxity in the skin.
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