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High-fat feeding disrupts daily eating behavior rhythms in obesity-prone but not in obesity-resistant male inbred mouse strains
High-fat diet changes daily eating patterns in male mice prone to obesity but not in those resistant to it
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Abstract
Male obesity-prone mice gained more weight and fat when fed a high-fat diet compared to obesity-resistant mice.
- Abnormal meal timing, such as late-night snacking, is linked to obesity in humans.
- Disruption of daily eating rhythms contributes to obesity in mice.
- Obesity-prone male mice showed a significant reduction in the daily rhythm of eating behavior when on a high-fat diet.
- Obesity-resistant male mice maintained their eating behavior rhythms despite high-fat diet feeding.
- High-fat feeding did not affect locomotor activity rhythms in either obesity-prone or obesity-resistant male mice.
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