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A high-sucrose diet does not enhance spontaneous metastasis of Lewis lung carcinoma in mice
A high-sugar diet does not increase lung cancer spread in mice
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Abstract
The high-sucrose diet does not enhance spontaneous metastasis of Lewis lung carcinoma in mice.
- There were no differences in energy intake among the high-sucrose, high-fat, and control diet groups.
- The high-sucrose group had a higher percent body fat mass than the control group but lower than the high-fat group.
- The number and size of lung metastases were significantly higher in the high-fat group compared to the control group.
- Measurements of lung metastases in the high-sucrose group were similar to those in the control group.
- Hepatic triacylglycerol levels and plasma concentrations of insulin and certain proinflammatory and angiogenic factors were significantly lower in the high-sucrose group than in the high-fat group.
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