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Abstract
Essence
Thermoneutral housing reshaped tissue-specific circadian mRNA rhythms in mouse heart, liver, and diaphragm.
Evidence
This RNA-seq mouse experiment sampled hearts, livers, and diaphragms every 4 hours over 48 hours in constant darkness, comparing room temperature at 25 C with thermoneutrality at 30 C.
Caveat
The findings are tissue transcript rhythms in mice under controlled housing temperatures, not direct evidence of physiological or clinical outcomes.
Simplified
Circadian Biology