Immunity around the clock

Nov 26, 2016Science (New York, N.Y.)

Daily rhythms in immune system activity

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Abstract

The circadian clock influences immune responses, potentially reducing associated costs.

  • Immunity is essential for defense against pathogens but can lead to harmful effects if overactivated.
  • Many immune parameters show daily rhythmic patterns, suggesting a link between the circadian clock and immune function.
  • Interactions between environmental cues and immune cell oscillators help optimize immune responses across the day.
  • Understanding how the circadian clock regulates immunity could reveal new strategies for managing infections and chronic inflammation.

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