The Body’s Internal Clock and Its Role in Immune System Function

Circadian rhythms regulate various physiological systems, including immune responses.

• The circadian clock influences innate immune responses and several aspects of adaptive immunity.
• Genetic and biochemical mechanisms connect immunity to the core circadian clock.
• Circadian oscillations may play a significant role in the regulation of the immune system.
• Insights into these mechanisms could inform vaccination strategies and the development of chrono-immunotherapy.

Simplified