Full text is available at the source.
Abstract
LANA achieved a detection limit of 50 pg/mL for cardiac troponin I (cTnI).
- The platform utilizes a light-activated mechanism to enhance signal sensitivity and control activation timing.
- It integrates immunomagnetic enrichment and aptamer-functionalized gold nanoparticles to improve detection performance.
- LANA demonstrated a wide dynamic range of 0.05-500 ng/mL for quantifying cTnI.
- This approach effectively reduces background activation, leading to more accurate readings.
- The design is modular and can be adapted for detecting various protein or small-molecule biomarkers.
Simplified