Night-Shift Work and Risk of Prostate Cancer: Results From a Canadian Case-Control Study, the Prostate Cancer and Environment Study

Jul 31, 2019American journal of epidemiology

Night-Shift Work and Risk of Prostate Cancer: Findings from a Canadian Study

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Abstract

No association was found between night-shift work and prostate cancer incidence in a study of 1,904 cases and 1,965 controls.

  • Night-shift work was defined as working at least 3 hours between midnight and 5:00 am for at least 3 nights per month over a year.
  • The study included detailed work histories from 15,724 job records collected through face-to-face interviews.
  • Analysis of night-shift work metrics did not reveal significant associations with overall prostate cancer or high-grade cancers.
  • No differences were observed between low-grade and high-grade cancers regarding exposure to night-shift work.
  • Sensitivity analyses, including stricter definitions of night-shift exposure, confirmed the lack of association.

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