Journal of clinical anesthesia

Managing surgery for patients using GLP-1 medicines: risks, advice, and future ideas

Updated

Abstract

Patients on glucagon-like peptide-1 receptor agonists (GLP-1RAs) may have an increased risk of gastric content retention during surgery.

  • GLP-1RAs are linked to delayed gastric emptying.
  • There is a potential risk for pulmonary aspiration in patients using GLP-1RAs during anesthesia.
  • Current evidence indicates that patients on GLP-1RAs may present with a full stomach when undergoing surgery.
  • Recommendations for managing these patients include careful medication assessment and additional monitoring.
  • Preventive measures such as pre-anesthesia gastric ultrasound and rapid sequence induction may be beneficial.
  • Further research is necessary to develop comprehensive guidelines for the perioperative management of patients taking GLP-1RAs.

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Funding

Competing interests

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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