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Abstract
Intestinal SARS-CoV-2 reservoirs disrupt VLCFA-mediated peroxisome signaling critical for epithelial repair in Long COVID patients.
- Long COVID is linked to ongoing gastrointestinal dysfunction.
- Intestinal reservoirs of SARS-CoV-2 may interfere with signaling pathways necessary for healing the gut lining.
- Research included patient studies as well as models in fruit flies and mammals to uncover the underlying mechanisms.
- FDA-approved peroxisome activators have been identified as potential treatments for this condition.
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