Polymorphism of the Oxytocin Receptor (OXTR) Gene Affects the Circulating Oxytocin Receptor Levels in Late-Term Pregnancy in a Turkish Population

Jun 15, 2020Gynecologic and obstetric investigation

Genetic Differences in the Oxytocin Receptor Affect Its Blood Levels in Late Pregnancy in Turkish Women

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Abstract

Serum oxytocin levels were 21.50 ± 10.69 ng/L in late-term pregnant women with the rs53576 GG genotype, compared to 62.71 ± 18.01 ng/L in term pregnant women.

  • No differences were found in the gene distributions of four common oxytocin receptor variants between late-term and term pregnant women.
  • Oxytocin receptor levels in the late-term group with the GG genotype were 17.92 ± 8.15 pg/mL, while in the term group they were 45.77 ± 11.66 pg/mL.
  • The rs53576 oxytocin receptor variant may influence serum oxytocin and receptor levels during late-term pregnancy.

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