Advantages of analyzing postmortem brain samples in routine forensic drug screening—Case series of three non-natural deaths tested positive for lysergic acid diethylamide (LSD)

LSD was detected in brain tissue at concentrations ranging from 0.34-10.8 μg/kg in three case reports.

• LSD and its metabolites were quantified in various biological samples, including brain tissue and blood.
• The concentration of LSD in brain tissue was higher than in peripheral blood.
• Additional psychoactive compounds were found, but all were below toxic levels.
• In two cases, the cause of death was drowning, while one involved a brain injury.
• The toxicological findings may provide insight into the decedents' inability to cope with fatal incidents.

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