The Knee

Recovery after knee replacement in type 2 diabetes patients treated with semaglutide versus tirzepatide

Updated

Abstract

Semaglutide and tirzepatide are increasingly prescribed to adults with type 2 diabetes undergoing total knee arthroplasty.

  • There is uncertainty regarding differences in short-term postoperative outcomes between semaglutide and tirzepatide.
  • Both medications target hormonal pathways that may influence metabolic responses.
  • The increasing use of these agents in T2DM patients undergoing surgery highlights a potential area for further investigation.

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