Use and uncertainties of GLP-1 and SGLT-2 treatments after pregnancy in women who had gestational diabetes

Approximately 14% of pregnancies are affected by gestational diabetes mellitus (GDM).

• GDM is linked to negative outcomes during pregnancy and a significantly higher risk of long-term cardiometabolic diseases.
• Women with a history of GDM have a ten-fold increased risk of developing type 2 diabetes mellitus (T2DM).
• The presence of early postpartum prediabetes may heighten the risk of T2DM in these women.
• Existing prevention strategies, such as lifestyle changes and metformin, have generally demonstrated limited success in preventing diabetes in this population.

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