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Psyllium husk powder enhances the management of type 2 diabetes by modulating gut microbiota and their metabolic products
Psyllium husk powder helps manage type 2 diabetes by changing gut bacteria and their metabolism
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Abstract
Plantain shell powder (PHP) significantly enhances blood glucose homeostasis and insulin sensitivity in T2DM mice.
- Higher doses of PHP resulted in optimal improvements in blood glucose control and insulin sensitivity.
- PHP reduced organ damage and helped regulate blood lipid levels and short-chain fatty acid concentrations.
- The treatment improved the ratio of Bacteroidota to Firmicutes and increased beneficial bacteria such as Bacteroidales and Muribaculaceae.
- PHP also enhanced key metabolic pathways, including those involved in fatty acid metabolism and signaling.
- Interactions between beneficial bacteria and metabolic pathways may be associated with improved metabolic function and reduced inflammation.
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