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New NMR Method to Measure Psilocybin and Psilocin Levels in Psychedelic Mushrooms
Updated
Abstract
Essence
A workflow quantified psilocybin and psilocin in dried psychedelic mushroom samples and revealed substantial alkaloid variability.
Evidence
This analytical method study tested an optimized extraction protocol and combined hydrogen and phosphorus qNMR on dried psychedelic mushroom samples, including user-provided and laboratory-grown material.
Caveat
The work validates a measurement method rather than clinical effects, and the observed variability may depend on sample source and storage conditions.
Simplified
Key numbers
0.154 to 0.456%
Range
Total tryptamine content as a percentage of dry biomass.
95%
Extraction Efficiency
Percentage of total psilocybin and psilocin recovered by the fourth extraction.
Psychedelic Science