Real-World Benefits and Costs of Nasal Esketamine Compared to Muscle-Injected Ketamine

Intramuscular ketamine was evaluated for non-inferiority to intranasal esketamine in treating treatment-resistant depression.

• Both ketamine and esketamine are used for treatment-resistant depression.
• The study aimed to compare the effectiveness and safety of these two administration routes.
• Healthcare costs associated with each treatment were also assessed.
• Findings on safety and cost differences were part of the evaluation.

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