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Robust food anticipatory circadian rhythms in rats with complete ablation of the thalamic paraventricular nucleus
Strong daily food-anticipation rhythms in rats without the brain's thalamic paraventricular nucleus
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Abstract
Rats with complete PVT ablation showed increased total daily activity but no change in food-anticipatory activity.
- Circadian rhythms related to food anticipation are not critically dependent on the thalamic paraventricular nucleus (PVT).
- Scheduled feeding impacted glucose utilization and gene expression in the PVT but did not affect food-anticipatory behavior in ablated rats.
- A previous study indicated that absence of the PVT resulted in no food anticipatory circadian activity rhythms.
- Despite increased overall activity, rats with PVT lesions did not exhibit changes in the timing or persistence of food-anticipatory activity.
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