Rotating night shift work and polymorphism of genes important for the regulation of circadian rhythm
Night shift work with changing hours and gene differences linked to body clock regulation
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Abstract
The frequency of women with the rare CRY1 TT genotype was 17.0% among rotating night shift workers compared to 13.9% among day workers.
- No significant differences were found in the genotypes of BMAL1, CLOCK, CRY2, PER1, PER2, and PER3 between rotating night and day workers.
- The CRY1 TT genotype was more common in rotating night shift workers, with a P-value of 0.06.
- The CRY1 TT genotype may be associated with the total duration of rotating shift work among women.
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