Journal of clinical psychopharmacology

Semaglutide and Similar Drugs for Treating Metabolic Problems Linked to Antipsychotic Use in Schizophrenia

Updated

Abstract

Individuals with schizophrenia spectrum disorders face significant metabolic abnormalities linked to their treatment.

  • Metabolic abnormalities are prevalent in individuals with schizophrenia spectrum disorders.
  • Antipsychotic treatment may worsen these metabolic issues.
  • Increased cardiovascular problems and early death are associated with these metabolic conditions.
  • GLP-1 receptor agonists have shown metabolic benefits in the general population.
  • The effectiveness and safety of GLP-1 receptor agonists for those with schizophrenia are not yet established.

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