European heart journal supplements : journal of the European Society of Cardiology

Semaglutide's role in heart, kidney, and metabolism health

Updated

Abstract

Semaglutide may reduce major adverse cardiovascular events in overweight or obese patients with high cardiovascular risk.

  • Semaglutide improves functional capacity in patients with heart failure and preserved left ventricular function.
  • It could slow the progression of albuminuria in diabetic populations.
  • There is a potential reduction in the risk of chronic kidney disease associated with semaglutide.
  • The drug's effects may stem from its anti-inflammatory properties and ability to lower blood pressure.
  • Weight reduction is another mechanism through which semaglutide may enhance cardiovascular and renal health.

Simplified

Key numbers

24%
Reduction in Major Adverse Cardiovascular Events
Compared to placebo in patients with Type 2 diabetes and cardiovascular disease.
24%
Reduction in Renal Events and Cardiovascular Death
In patients with chronic kidney disease.

Full Text

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Funding

Competing interests

Conflict of interest: none declared.
PubMed

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