Cardiovascular & hematological disorders drug targets

Using SGLT-2 Inhibitors and GLP-1 Receptor Agonists to Manage Metabolic Syndrome in Type 2 Diabetes

Updated

Abstract

Metabolic syndrome (MetS) is closely linked with type 2 diabetes mellitus (T2DM), increasing cardiovascular and metabolic disease risk.

  • MetS includes features such as central obesity, high triglyceride levels, low HDL cholesterol, high blood pressure, and impaired fasting glucose.
  • The relationship between MetS and T2DM is bidirectional, meaning each condition can influence the other.
  • Sodium-glucose co-transporter-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists may help manage issues associated with MetS.
  • These medications could improve blood sugar control and offer potential benefits for heart and kidney health in individuals with T2DM.

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