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Abstract
Aging affects human physiology, resulting in reduced organ function and increased susceptibility to chronic diseases.
- Cellular senescence is a key aspect of aging that connects molecular damage to inflammation, impacting skin structure and function.
- Chronic inflammation, referred to as inflammaging, may hinder skin regeneration and accelerate aging processes.
- Advanced skin aging can lead to significant atrophy, chronic fragility, and impaired wound healing.
- Diminished immunosurveillance in aged skin may increase vulnerability to infections and injuries.
- Understanding skin aging involves exploring the links between skin health and systemic inflammation, revealing knowledge gaps for future research.
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