We can’t show the full text here under this license.
Using Skin Models to Study Protein Balance and Early Signs of Aging
Updated
Abstract
Essence
Skin may help reveal early changes that precede visible features of skin aging.
Evidence
This perspective review discusses human epidermal and full-thickness skin organoid models and emerging findings on protein folding, proteasomal activity, autophagy, sebocyte proteostasis, and inflammaging.
Caveat
The article synthesizes early model-system insights and emphasizes conceptual challenges and experimental limitations rather than reporting definitive intervention outcomes.
Simplified