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Causal dynamics of sleep, circadian rhythm, and mood symptoms in patients with major depression and bipolar disorder: insights from longitudinal wearable device data
How sleep, daily body clock, and mood symptoms influence each other over time in people with major depression and bipolar disorder using wearable device data
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Abstract
Causality from circadian phase disturbance to mood symptoms was found in 66.7% of patients with major depressive disorder and 85.7% of patients with bipolar disorder type I.
- Circadian phase disturbances may precede mood symptoms in patients with mood disorders.
- No causal relationship was found between sleep phase disturbances and mood symptoms.
- The analysis included data from 139 patients with mood disorders, monitored over more than 40,000 days.
- Causality was not observed in patients with bipolar disorder type II.
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