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Sleep Disorders and Inflammatory Disease Activity: Chicken or the Egg?
The relationship between sleep problems and inflammation: which comes first?
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Abstract
Sleep dysfunction is associated with increased inflammatory cytokines in patients with inflammatory bowel disease (IBD).
- Sleep dysfunction may lead to an upregulation of inflammatory cytokines.
- Increased inflammatory cytokines are linked to disease flares in IBD.
- Disruption of the circadian rhythm could contribute to IBD symptoms.
- There is a potential risk of malignancy associated with sleep dysfunction in IBD patients.
- Further research is needed to explore therapeutic interventions targeting sleep and circadian rhythm optimization.
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