Stripe Rust Protein Pst08755 Blocks Wheat Immune Response by Targeting a Key Wheat Cell Signaling Protein

Stable overexpression of TaRLCK176 in wheat confers broad-spectrum resistance against wheat stripe rust.

• Wheat stripe rust is caused by the pathogen Puccinia striiformis f. sp. tritici (Pst), impacting global wheat production.
• TaRLCK176, a wheat protein, plays a positive role in enhancing resistance to Pst.
• The effector Pst08755 from Pst targets TaRLCK176, leading to its degradation.
• Degradation of TaRLCK176 suppresses the activation of certain immune responses in wheat.
• These findings reveal a mechanism by which Pst can evade wheat immunity.

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