We can’t show the full text here under this license. Use the link below to read it at the source.
Synaptic targets of circadian clock neurons influence core clock parameters
Connections of body clock neurons affect key timing functions
AI simplified
Abstract
Silencing synaptic output from SLP316 neurons shortened the free-running period in circadian rhythm regulation.
- Ventral lateral neurons (sLNs) are critical pacemakers in the circadian clock network.
- sLNs form strong synaptic connections with SLP316 neurons, which were previously uncharacterized.
- Silencing SLP316 neurons led to reduced daytime activity and increased daytime sleep.
- Hyperexciting SLP316 neurons resulted in lengthening of the free-running period.
- The findings suggest that SLP316 neurons, a nonclock cell type, may play a role in regulating sleep and activity timing.
AI simplified