The role of insufficient sleep and circadian misalignment in obesity

Oct 25, 2022Nature reviews. Endocrinology

How Not Enough Sleep and Body Clock Problems Are Linked to Obesity

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Abstract

Insufficient sleep and circadian misalignment may contribute to poor metabolic health and increased weight gain.

  • Insufficient sleep is defined as sleeping less than the recommended amount for health benefits.
  • Circadian misalignment occurs when individuals are awake and consume food during times when their internal body clock promotes sleep.
  • Insufficient sleep and circadian misalignment are linked to changes in appetite hormones, such as ghrelin, leptin, and peptide-YY.
  • These factors may affect energy expenditure and influence food intake and choices.
  • Millions globally fail to obtain adequate sleep, which is essential for healthy metabolic functions.
  • Modern lifestyles, including late-night screen use and shift work, often disrupt sleep patterns and circadian health.

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