Big metabolic improvement with tirzepatide in a patient with partial fat loss after stem cell transplant

Acquired lipodystrophy may be associated with severe insulin resistance and metabolic complications.

• The disorder is characterized by loss or dysfunction of adipose tissue.
• Metabolic complications have been reported following hematopoietic stem cell transplantation.
• Clinical features and optimal treatment strategies for these complications remain poorly defined.
• Tirzepatide is a dual agonist targeting specific receptors and has been introduced as a potential therapy for type 2 diabetes.

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