Characterization of transforming growth factor beta regulator 1-like and association between its expression levels and growth of the giant tiger shrimp Penaeus monodon

The full-length cDNA of transforming growth factor beta regulator 1-like (PmTbrg1-l) in the giant tiger shrimp Penaeus monodon was identified as 1184 bp long.

• RNA interference targeting PmTbrg1-l resulted in reduced levels of both PmTbrg1-l and myostatin in hemocytes compared to controls.
• Juveniles with single nucleotide polymorphism pattern III (A/A) displayed greater average body weight and total length compared to patterns II (G/G) and IV (A/G).
• Expression levels of PmTbrg1-l were significantly higher in the hepatopancreas of female shrimp than in males.
• Larger juveniles exhibited significantly higher expression levels of PmTbrg1-l compared to medium and small juveniles.
• Findings suggest that PmTbrg1-l may be functionally related to growth in Penaeus monodon.

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