Use of once‐weekly semaglutide in patients with type 2 diabetes in routine clinical practice: Results from the SURE C anada multicentre, prospective, observational study

Jun 18, 2021Diabetes, obesity & metabolism

Once-weekly semaglutide use in people with type 2 diabetes during regular medical care: Results from a Canadian multi-center study

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Abstract

In total, 452 patients initiated semaglutide, with a mean baseline HbA1c of 8.1%.

  • Mean HbA1c was reduced by 0.9%-point at the end of the study.
  • Mean body weight decreased by 4.3 kg by the end of the study.
  • At the end of the study, 46.9% of patients achieved an HbA1c of less than 7.0%.
  • 40.9% of patients achieved a weight loss of 5% or higher.
  • 24.1% of patients met the composite endpoint of HbA1c reduction of 1% or more and weight loss of 3% or more.
  • Patient-reported outcomes improved from baseline to the end of the study, with no new safety concerns reported.

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Key numbers

0.9%-point
HbA1c Reduction
Mean change from baseline HbA1c of 8.1%
4.3 kg
Weight Loss
Mean change in body weight
46.9%
Achieved HbA1c Target
Patients achieving HbA1c <7% at end of study

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