Association of Healthy Lifestyle Behaviours With Incident Inflammatory Bowel Disease: A Population‐Based Prospective Cohort Study

Feb 17, 2025Alimentary pharmacology & therapeutics

Healthy lifestyle habits linked to new cases of inflammatory bowel disease in a large population study

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Abstract

Having 3-5 healthy lifestyle behaviours is associated with a 50% lower incidence of inflammatory bowel disease (IBD).

  • Participants with 1, 2, and 3-5 healthy lifestyle behaviours had hazard ratios of 0.75, 0.72, and 0.50 for IBD incidence, respectively.
  • A trend was observed indicating that more healthy behaviours correspond to lower IBD incidence (p for trend < 0.001).
  • Similar associations were found for both Crohn's disease and ulcerative colitis.
  • Never smoking was the only behaviour with a significant independent inverse association with overall IBD incidence (HR 0.70).
  • Never smoking also showed a strong inverse association with the incidence of ulcerative colitis (HR 0.58).

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