Daily body clock genes show that regulation after gene activation plays a role in mammals

Circadian clock regulation involves thousands of mRNAs and proteins to maintain daily cycles.

• Circadian rhythms require precise timing in mRNA and protein expression.
• Post-transcriptional regulation plays a significant role in determining protein levels after mRNA production.
• This regulation allows cells to adjust protein levels quickly without needing to create new transcripts.
• The contribution of circadian post-transcriptional mechanisms to overall gene expression remains unclear.
• New insights from circadian genomics highlight the complexity of rhythmic regulation in mammals.

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