Interactions between disrupted body clocks and tumor growth, metabolism, and immune response

Long-term disruptions in circadian rhythms may impact cellular health and are associated with various health problems, including cancer.

• Circadian rhythm is a 24-hour system that regulates sleep, metabolism, hormone function, and immune responses.
• Disruptions from factors like shift work and jet lag can lead to a loss of normal cell growth regulation at the genetic level.
• This loss of regulation is linked to tumorigenesis and affects the body's ability to manage cancer cell detection and elimination.
• Circadian rhythm influences cellular functions related to cancer progression and immune cell activity.
• Understanding the interaction between circadian disruption and cancer may optimize the timing of tumor therapies and improve treatment outcomes.

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