Rhythms in your bones: how circadian rhythms impact bone cell function and skeletal health

Circadian rhythms significantly influence the formation, resorption, and remodeling of bone tissue.

• Bone cells have internal clocks that help regulate the timing of bone processes.
• The balance between bone formation and resorption is affected by these internal clocks.
• External factors, such as hormones and mechanical forces from exercise, also impact bone-cell activity.
• Recent advances highlight the interaction of intrinsic and extrinsic timing cues in skeletal health.
• Understanding bone circadian biology could lead to new therapeutic strategies for improving bone health.

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