Impact of circadian and diurnal rhythms on cellular metabolic function and neurodegenerative diseases

Aug 3, 2020International review of neurobiology

How daily and internal body clocks affect cell metabolism and brain diseases

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Abstract

The circadian clock regulates various biological functions, including hormone levels and cognitive function.

  • The circadian clock is involved in optimizing biological functions for specific times of the day.
  • Sleep-wake cycles are the most visible outputs of the circadian clock.
  • Disruption of circadian rhythms and sleep may be linked to neurodegenerative diseases.
  • There is evidence suggesting that the circadian clock may influence metabolic pathways.
  • Connections between the circadian clock, metabolism, and neurodegenerative disease are proposed.

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