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Circadian Rhythms, Sleep, and Disorders of Aging
Body Clock, Sleep, and Aging-Related Problems
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Abstract
Sleep-wake cycles are disrupted in people with neurodegenerative disorders.
- Data from animal models support the observation that disrupted sleep and circadian regulation occur in these disorders.
- There is a potential link between disrupted sleep patterns and the loss of neural function.
- Normal aging also affects circadian rhythms and sleep consolidation, which may increase the risk of disorders like Alzheimer's disease.
- The mechanisms connecting circadian/sleep dysregulation to neurodegeneration are not yet fully understood.
- Considering treatment for circadian and sleep disruptions could help alleviate symptoms associated with neurodegenerative disorders.
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