Coupled oscillators control morning and evening locomotor behaviour of Drosophila

Oct 16, 2004Nature

Linked biological clocks control morning and evening movement in fruit flies

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Abstract

The timing of morning and evening activity in Drosophila melanogaster is regulated by two distinct groups of circadian neurons.

  • Morning activity is controlled by ventral lateral neurons expressing the neuropeptide PDF.
  • Evening activity arises from a different group of neurons, including dorsal lateral neurons.
  • Both neuronal groups can operate independently but are functionally linked.
  • Cell-specific ablation techniques reveal the distinct roles of these neuronal populations in regulating daily rhythms.

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