Full text is available at the source.
Mode of action of dopamine in inducing hyperglycemia in the fresh water edible crab, Oziothelphusa senex senex
How dopamine causes high blood sugar in the freshwater edible crab Oziothelphusa senex senex
AI simplified
Abstract
Dopamine injection produced hyperglycemia in intact crabs in a dose-dependent manner.
- Hyperglycemia was associated with a significant decrease in total carbohydrates and glycogen levels in intact crabs.
- Dopamine increased glycogen phosphorylase activity in the hepatopancreas and muscle of intact crabs, suggesting dopamine-induced glycogen breakdown.
- Bilateral eyestalk ablation led to increased total carbohydrates and glycogen levels, along with decreased phosphorylase activity.
- Eyestalk ablation resulted in lower levels of hyperglycemic hormones in the hemolymph.
- Dopamine-injected crabs had higher hemolymph hyperglycemic hormone levels compared to control crabs, indicating a stimulating effect of dopamine.
AI simplified