Melatonergic regulation of hemolymph sugar levels in the freshwater edible crab, Oziotelphusa senex senex

Feb 9, 2010Journal of experimental zoology. Part A, Ecological genetics and physiology

Melatonin's role in controlling blood sugar in the freshwater edible crab

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Abstract

Melatonin injection induced hyperglycemia in the freshwater edible crab, Oziotelphusa senex senex, in a dose-dependent manner.

  • Both intact and eyestalk-ablated crabs exhibited hyperglycemia after melatonin administration.
  • Bilateral eyestalk ablation significantly increased total carbohydrates and glycogen levels.
  • Phosphorylase activity decreased in the hepatopancreas and muscle of crabs following eyestalk ablation.
  • Melatonin injection led to a significant decrease in total carbohydrate and glycogen levels.
  • Increased phosphorylase activity in the hepatopancreas and muscle was observed after melatonin injection in both crab types.
  • Melatonin-induced hyperglycemia appears not to be mediated by eyestalk hyperglycemic hormone.

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