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Eveningness is associated with more severe depressive symptoms independently of sleep quality and fatigue level only in first-episode but not recurrent depression in major depressive disorder
Evening preference is linked to worse depression symptoms in first-time but not repeated episodes of major depression, regardless of sleep quality and tiredness
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Abstract
In a study of 386 major depressive disorder patients, evening chronotype significantly predicted increased depressive severity only in those with a first episode.
- Evening chronotype is linked to higher depressive severity in first-episode major depressive disorder patients.
- The association between chronotype and depressive severity was not observed in patients experiencing recurrent episodes.
- Sleep quality and fatigue level were also connected to depressive severity in these patients.
- Circadian-focused treatment may be beneficial specifically for individuals with first-episode depression.
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