How internal body clocks and daily rhythms relate to eating habits

Phase shifting responses to light are correlated with induction of Per1 and Per2 within the suprachiasmatic nuclei.

• The master circadian clock in mammals is primarily reset by light stimuli.
• Peripheral oscillators are synchronized by the suprachiasmatic clock when food is available ad libitum.
• Temporal restricted feeding serves as a significant synchronizer for peripheral oscillators but does not affect the suprachiasmatic clock.
• Timed calorie restriction can alter the temporal organization of the suprachiasmatic nuclei and its light-dark cycle synchronization.
• Conflicts between light and feeding cues can modify clock gene expression and circadian outputs.

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