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Gènes d'horloge, rythmes circadiens et prise alimentaire
How internal body clocks and daily rhythms relate to eating habits
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Abstract
Phase shifting responses to light are correlated with induction of Per1 and Per2 within the suprachiasmatic nuclei.
- The master circadian clock in mammals is primarily reset by light stimuli.
- Peripheral oscillators are synchronized by the suprachiasmatic clock when food is available ad libitum.
- Temporal restricted feeding serves as a significant synchronizer for peripheral oscillators but does not affect the suprachiasmatic clock.
- Timed calorie restriction can alter the temporal organization of the suprachiasmatic nuclei and its light-dark cycle synchronization.
- Conflicts between light and feeding cues can modify clock gene expression and circadian outputs.
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