Use of glucagon-like peptide-1 drugs before hospital does not lower opioid use but is linked to shorter hospital stays after joint replacement surgery

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) may influence perioperative pain and opioid use after total joint arthroplasty.

• GLP-1RAs are believed to have potential benefits in reducing inflammation, pain, and addiction.
• The study investigates their specific effects on acute pain management following surgery.
• Opioid consumption during the recovery period may be affected by the use of GLP-1RAs.

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