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Association of healthy sleep patterns with incident sepsis: a large population-based prospective cohort study
Healthy Sleep Patterns Linked to Lower Risk of Developing Sepsis in a Large Population Study
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Abstract
During a mean follow-up of 13.54 years, 13,357 (3.26%) incident cases were recorded among 409,570 participants.
- Each one-point increase in a composite sleep score is associated with a 5% lower risk of developing sepsis.
- Participants with a of 5 had a 24% lower risk of sepsis compared to those with scores of 0-1.
- The association between healthy sleep patterns and reduced sepsis risk is stronger in individuals aged under 60 years.
- No significant association was found between healthy sleep patterns and sepsis-related death or critical care admission.
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Key numbers
13,357
Incident Cases
Total cases recorded during a mean follow-up of 13.54 years
5%
Lower Risk per Score Point Increase
Risk reduction associated with each one-point increase in
0.76
of 5 Risk
Multivariate-adjusted hazard ratio for with a score of 5 vs. 0-1