The twilight of the immune system: The impact of immunosenescence in aging

Apr 9, 2021Maturitas

How Aging Weakens the Immune System

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Abstract

Cellular senescence is linked to a wide range of age-related diseases.

  • Accumulation of senescent cells with age is associated with various pathologies.
  • Immunosenescence affects immune cells and contributes to physiological changes in older adults.
  • This process is connected to increased inflammation, susceptibility to infections, and higher rates of cancer in the elderly.
  • Immunosenescence may also play a role in the development of autoimmune diseases.
  • Understanding immunosenescence could enhance disease prevention and treatment strategies for older populations.

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